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Archive for the Category ‘Study Material’

Pregabalin approved for neuropathic pain

Pregabalin approved for neuropathic pain

The US Food and Drug Administration (FDA) has approved pregabalin (Lyrica, Pfizer Inc.) for the management of neuropathic pain associated with spinal cord injury.

Glaucoma & Preventive Measures

Glaucoma & Preventive Measures

GLAUCOMA ???? Glaucoma is an eye disorder in which internal eye pressure (Intraocular pressure-IOP) is very high. In this condition, eye has too much aqueous humor pressure either because of over production of fluid or of improper draining. This leads to damage of optic nerve results in Vision loss. This nerve acts like an electric [...]

The 6 Best Supplements for Strong Teeth

The 6 Best Supplements for Strong Teeth

To prevent receding of gum: Regular Brush, floss, eat right and take a couple of extra nutrients. Here are the six best supplements for strong teeth and healthy gums: CoQ10: Every day, you chew a supplement that contains 60mg of coenzyme Q10, or CoQ10, an antioxidant that helps maintain the soft tissues in your body-including [...]

Vitamin K for Osteoporosis

Vitamin K for Osteoporosis

Vitamin K for Osteoporosis

MIFEPRISTONE

MIFEPRISTONE

Mifepristone is a synthetic 19-nor steroid compound with a bulky p-(dimethylamino)phenyl substituent above the plane of the molecule at the 11β-position responsible for inducing or stabilizing an inactive receptor conformation and a hydrophobic 1-propynyl substituent below the plane of the molecule at the 17α-position that increases its progesterone receptor binding affinity.

Stability of ferrous Ascorbate and its significance for Iron Absorption

Stability of ferrous Ascorbate and its significance for Iron Absorption

Ferrous Ascorbate is a synthetic molecule of ascorbic acid and iron.

Ascorbic acid enhances absorption of iron. Ascorbic acid reduces ferric iron to ferrous iron which remains soluble even at neutral pH.

Omega-3 Fatty Acids

Omega-3 Fatty Acids

Omega-3 fatty acids are considered essential fatty acids. Also known as polyunsaturated fatty acids (PUFAs).They are necessary for human health but the body cannot make them –have to get them through food. Omega-3 fatty acids can be found in fish, such as salmon, tuna, and halibut, other seafood including algae and krill, some plants, and nut oils.

Vitamin D – A brief

Vitamin D – A brief

Cholecalciferol is preferred in patients with normal or mild renal impairment (GFR > 60 mL/min) with a normal intact PTH level.
In the presence of secondary hyperparathyroidism, which usually begins in stage 3 or 4 of CKD (GFR 30-59 mL/min and 15-29 mL/min, respectively), the preferred agent for supplementation is an activated vitamin D sterol (eg, calcitriol).

Ursodeoxycholic acid

Ursodeoxycholic acid

Ursodeoxycholic acid (UDCA) is used in the treatment of cholestatic liver diseases, gallstone dissolution, and for patients with hepatitis C virus infection to ameliorate elevated alanine aminotransferase levels. The efficacy of UDCA treatment has been debated and the mechanisms of action in humans have still not defined. Suggested mechanisms include the improvement of bile acid transport and/or detoxification, cytoprotection, and anti-apoptotic effects.

Febuxostat

Febuxostat

Febuxostat is an inhibitor of xanthine oxidase that is indicated for use in the treatment of hyperuricemia and gout. Febuxostat is a non-purine selective inhibitor of xanthine oxidase. It works by non-competitively blocking the channel leading to the active site on xanthine oxidase. Xanthine oxidase is needed to successively oxidize both hypoxanthine and xanthine to [...]

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